Nexus Medical has been around for over 20 years to solve the many unintended consequences of unintentional blood reflux in Intravenous (IV) Catheters. Nexus developed the Nexus TKO® (“To Keep Open”) Anti-Reflux Diaphragm to provide true anti-reflux protection. Using an anti-reflux needle-free (NF) connector has been proven to result in the least amount of blood reflux into the catheter1,6.
According to the 2024 INS Infusion Therapy Standards of Practice, a neutral NF connector is no longer a category, but listed as a definition on how a NF connector is expected to function. Anti-reflux NF connectors are the only the way to achieve this and recommended by the INS Infusion Therapy Standards of Practice2.
The Nexus TKO® Anti-Reflux Diaphragm will protect your IV catheter from unintentional blood reflux. This 24/7 protection results from the patented diaphragm which automatically opens and closes based upon infusion pressure from gravity IV containers, infusion pumps, and flushing syringes. The reduction of unintentional blood reflux into your IV catheter has been shown to
- Reduce occlusions by 48%3.
- Reduce t-PA usage from occlusions by 71%4
- Reduce CLABSI rates 36%5
- Cut waste cost associated by 41%4
- Extend the life of the catheter during hospital length of stay by 89%6,7

