Nexus TKO®
Technology

“Anti-reflux needleless connectors containing a bidirectional, pressure-sensitive diaphragm have the least amount of reflux”

2021 Infusion Therapy Standards of Practice (8th edition)

Why Nexus TKO®

Nexus TKO® To Keep Open is engineered to produce the least amount of blood reflux and IV catheter occlusions which meets the 2021 INS Standards of Practice.

TKO Pressure Activated Anti-Reflux diaphragm automatically opens and closes based upon physiological and mechanical pressure changes which prevents unintentional blood reflux without any change in clinical practice.


Nexus TKO® Difference

Nexus TKO has a 3-position pressure activated silicone diaphragm which provides bi-directional flow control and meets the definition for Anti-Reflux Needless Connectors in the 2021 Infusion Therapy Standards of Practice.

The TKO has a proprietary 3-position silicone diaphragm which opens and closes based upon mechanical and physiologic pressure changes in a closed IV system.


Nexus TKO® Performance

Evidence indicates that traditional needleless connectors, such as negative displacement, positive displacement and neutral, do not have the least amount of reflux, according to the 2021 INS Standards [36.B.3].

Anti-Reflux technology has the least amount of reflux due to the internal mechanism which is a 3-position pressure-activated silicone diaphragm.

Select your needleless connector below.
How does it compare to TKO?

Needleless Connector Results: Ranked by Reflux Amount

  • Reflux, Amount of Fluid/Blood pulled into a Catheter Lumen
  • Infusion, Amount of Fluid/Infusate pushed into a Vein

22 gauge PIV; 1” of Catheter = 8.42µL (+/-0.5µL) 1µL = 1mm3

  • |
    100
  • |
    75
  • |
    50
  • |
    25
  • |
    0
  • |
    0
  • |
    25
  • |
    50
  • |
    75
  • |
    100

22 gauge PIV; 1” of Catheter = 8.42µL (+/-0.5µL) 1µL = 1mm3

Figure adapted with permission from Author (2021); copyright 2020 Journal of the Association of Vascular Access.
Gibson M. Do Needleless Connector Manufacturer Claims on Bidirectional Flow and Reflux Equate to In Vitro Quantification of Fluid Movement? Journal of the Association for Vascular Access (2020) 25 (4): 28–36

Designed to Protect

TKO 3-Position Diaphragm prevents unintentional blood reflux from mechanical and physiological pressure changes in closed IV system

Microbial Protection

TKO Tri-Seal™ Design is validated and provides 3-Levels of Microbial Barrier Protection for your patient’s

Proven Performance

TKO performance is documented in over 25-studies demonstrating efficacy and improvements in patient outcomes, safety and satisfaction


Nexus Medical Products

Nexus Medical offers a wide array of IV products for acute care, home infusion, long-term care, neonatal, pediatric, pharmacy, EMS patients and more.

We offer a wide range of IV product sets, including filter, blood collection, administration, gravity and secondary sets, as well as flow regulators, and single, bifurcate, trifurcate or quadfurcate extension set configurations. Our soft, flexible tubing is designed for ease of use and power injectable to 325psi or 10 mL per second. Tubing sizes include microbore, standard bore, minibore and ultra-microbore.

NEXUS TKO-6P HV WITH GREEN GRIP FOR HOME INFUSION

NEXUS TKO NEONATAL EXTENSION SETS

NEXUS TKO POWER INJECTION EXTENSION SETS


Nexus TKO® Product Resources

Nexus offers a wide range of virtual and face-to-face educational resources for healthcare providers and patients. Gain access to presentations for continuing education, podcasts, posters, and other materials.

Get 24/7 IV Protection

Reduce the occurrences of occlusions and infiltrates and the high cost of tPA, Heparin and IV catheter replacements.

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