Nexus TKO®

“The design of your needle free connector plays a substantial role in your ability to limit hospital-acquired bloodstream infections (HA-BSA).”

– William R. Jarvis, MD

Nexus TKO® Design and Functionality

TKO is designed to protect both ends of your patient’s IV catheter from unintentional blood reflux and microbial ingress.

TKO Anti-Reflux technology is designed to provide Bi-Directional Flow Control which is proven to prevent unintentional blood reflux from physiological and mechanical pressure changes which occur in a closed IV System.

The TKO Tri-Seal® design has 3-independent sealing surfaces. These 3-independent sealing surfaces have been validated by an outside GLP Laboratory to provide a safe, swabbable protective barrier to microbial ingress.

Nexus TKO® 3-Position Silicone Diaphragm

The Nexus TKO® Anti-Reflux diaphragm automatically opens and closes based upon infusion pressure.

The TKO diaphragm automatically opens towards the patient when fluid pressure overcomes the patient’s vascular pressure from sources such as an IV pump, gravity IV containers, syringes, and pressure cuffs.

When the fluid pressure drops below the patient’s vascular pressure the TKO diaphragm instantly and automatically closes preventing unintentional blood reflux into the patient’s IV catheters.


The TKO Diaphragm provides Blood Reflux Protection 24/7™!


The TKO Diaphragm opens forward to safely infuse


The TKO Diaphragm opens in reverse for safe blood sampling

Tri-Seal™ Design Provides Microbial Barrier Protection

The Nexus TKO® Tri-Seal™ has been validated using 4-separate study groups with 4-separate bacteria by an outside GLP laboratory using a 96-activation protocol over 96-hours with three 18-hour incubation cycles.





The Nexus TKO®-6P Tri-Seal™ Design Provides 3-Levels of Microbial Barrier Protection 24/7™

Nexus TKO® is Designed with a Direct Fluid Pathway

TKO Anti-Reflux technology is designed with a clear, direct, rigid internal fluid pathway.

“Needleless connector with a direct – that is, straight – fluid
pathway that facilitates adequate flushing and reduces the
internal surface from biofilm development.”

– William R. Jarvis, MD

Nexus TKO® Product Resources

Nexus offers a wide range of virtual and face-to-face educational resources for healthcare providers and patients. Gain access to presentations for continuing education, podcasts, posters, and other materials.

Get 24/7 IV Protection

Reduce the occurrences of occlusions and infiltrates and the high cost of tPA, Heparin and IV catheter replacements.